Article
Transcriptomic Profiling Reveals Potential Genes Involved in the Immune Landscape of Polycystic Ovary Syndrome: An Exploratory Study
24 Jun 2025
Abstract excerpt
BACKGROUND: Polycystic ovary syndrome (PCOS) is a complex endocrine disorder associated with chronic inflammation, insulin resistance, and ovarian dysfunction. Emerging evidence implicates granulosa cell anoikis, a specialized form of apoptosis induced by extracellular matrix detachment, in PCOS pathogenesis. However, the involvement of anoikis-related genes (ARGs) remains poorly understood. METHODS:...
