Article

Analysis of expressed sequence tags mapping to the critical region of the 5q syndrome

2002-01-01

Abstract excerpt

The 5q- syndrome is a myelodysplastic syndrome characterised by a macrocytic anaemia, hypolobulated megakaryocytes, a low risk of transformation to AML, and a 5q- chromosome as the sole karyotypic abnormality. The approximate 5Mb critical region of gene loss of the 5q- syndrome has been defined in two patients with the 5q- syndrome at 5q31-q33, flanked by the genes for <i>FGF1</i> and <i>IL12ß</i>. The frequent lo...

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Literature Corpus work: cf0b783e-b635-551f-8a34-449dc9aecfcf
DOI: 10.21954/ou.ro.0000e808

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