Article

In Silico Evaluation of Inhibitors of Plasmodium Falciparum AP2-I Transcription Factor and Plasmodium Falciparum Bromodomain Protein 1

2022-02-04

Abstract excerpt

<h4>Background: </h4> Recent treatment failures observed for Artemisinin-based combination therapy (ACT) have raised concerns about the efficacy of the front-line drug to treat malaria and the need to develop a new antimalarial drug regimen. Plasmodium falciparum Apicomplexan Apetala 2 Invasion ( Pf AP2-I) transcription factor (TF) is a protein that regulates the expression of a subset of gene families involved in...

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Literature Corpus work: cf0598e1-3243-55b7-8e1d-6b660b2418de
DOI: 10.21203/rs.3.rs-1318124/v1

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