Article

Quantitative translation of dog-to-human aging by conserved remodeling of epigenetic networks

2019-11-04

Abstract excerpt

<h4>SUMMARY</h4> Mammals progress through similar physiological stages during life, from early development to puberty, aging, and death. Yet, the extent to which this conserved physiology reflects conserved molecular events is unclear. Here, we map common epigenetic changes experienced by mammalian genomes as they age, focusing on evolutionary comparisons of humans to dogs, an emerging model of aging. Using targe...

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Literature Corpus work: ced3b71d-cd2a-52e3-9a33-d11a64757aa7
DOI: 10.1101/829192

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