Non-Human Primates as a Comprehensive Model for Studying Epigenetic Markers of Aging

Abstract excerpt

Non-human primates (NHPs) serve as indispensable models for aging research due to their evolutionary proximity to humans, conserved epigenetic mechanisms, and lifespans amenable to longitudinal investigation. This review synthesizes age-related epigenetic modifications in NHPs, including DNA methylation, histone modifications, chromatin remodeling, and non-coding RNA regulation, and evaluates their alignment with...

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