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Development of multi-epitope chimeric antigens for scrub typhus diagnostics and vaccines: An in-silico investigation

2022-03-31

Abstract excerpt

Scrub typhus is a zoonotic bacterial disease caused by Orientia tsutsugamushi and accounts for up to 20% of common febrile illnesses and hospitalizations. The main obstacle to vaccine development is the lack of identification of relevant immunodominant antigens that stimulate broad-spectrum immune responses, including antibody, CD4 + T cells, and CD8 + T cells production. We examined the 56-kDa type-specific cell...

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Literature Corpus work
cec3c37e-7f2d-5595-8117-c5121a20bbb4
DOI
10.21203/rs.3.rs-1486762/v1
Open publication

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Development of multi-epitope chimeric antigens for scrub typhus diagnostics and vaccines: An in-silico investigationDOI 10.21203/rs.3.rs-1486762/v1
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