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Article

Dual-Antigen Subunit Vaccine Nanoparticles for Scrub Typhus

25 Nov 2023

Abstract excerpt

Orientia tsutsugamushi is the causative pathogen of scrub typhus, an acute febrile disease prevalent in the Asia–Pacific region that is spread to people through chigger bites. Despite the emerging threat, there is no currently available vaccine against O. tsutsugamushi. Here, we developed dual-antigen subunit vaccine nanoparticles using recombinant 47 kD and 56 kD proteins, which are immunogenic outer membrane...

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PMID: 38133275
DOI: 10.3390/pathogens12121390

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