Article
Mixed genotypes of Orientia tsutsugamushi in conserved genes and a single immune-dominant tsa56 genotype discovered from a patient with scrub typhus in Hainan Island, China: a case report.
BMC infectious diseases - 19 Aug 2022
Tang Chuanning, Zhang Liyuan, Huang Yi, Mai Wenhui, Xue Liying, Wang Gaoyu, Wen Shu, Peng Ruoyan, Wu Kunliang, Tian Xiuying, Pei Hua, Du Jiang, Yuen Kwok-Yung, Chan Jasper Fuk-Woo, Du Yongguo, Yin Feifei
Abstract excerpt
BACKGROUND: Orientia tsutsugamushi (O. tsutsugamushi), an obligate intracellular bacterium, is transmitted to humans through infected larval trombiculid mite bites, causing scrub typhus. Mixed genotypes of O. tsutsugamushi in canonical conserved genes were reported in 8-25% of blood samples from patients. Yet, there are few clinical descriptions of these mixed O. tsutsugamushi-infected patients. CASE...
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