Article

Methods to investigate intrathecal adaptive immunity in neurodegeneration

2021-01-04

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Cerebrospinal fluid (CSF) provides basic mechanical and immunological protection to the brain. Historically, analysis of CSF has focused on protein changes, yet recent studies have shed light on cellular alterations. Evidence now exists for involvement of intrathecal T cells in the pathobiology of neurodegenerative diseases. However, a standardized method for lo...

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Literature Corpus work: ce819888-26e5-5e1e-bdcf-1e7dff95179e
DOI: 10.21203/rs.3.rs-51188/v2

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