Article

Exploring the Molecular Pathways of Intracranial Aneurysm Formation in Autosomal Dominant Polycystic Kidney Disease Using Proteomic Analysis

2024-11-08

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Intracranial aneurysm (IA) frequently coincides with autosomal dominant polycystic kidney disease (ADPKD), exhibiting incidence rates nearly 10 times higher than the general population. However, the exact mechanism of how these two conditions is related remains unclear. This study aims to identify mechanisms behind IA occurrence in ADPKD patients using proteomics and to disc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ce2dee2e-0ec6-5be0-965b-97e8f1a799ee
DOI: 10.1101/2024.11.07.24316796

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Exploring the Molecular Pathways of Intracranial Aneurysm Formation in Autosomal Dominant Polycystic Kidney Disease Using Proteomic AnalysisDOI 10.1101/2024.11.07.24316796Read

Impact of Kidney Function and Kidney Volume on Intracranial Aneurysms in Patients with Autosomal Dominant Polycystic Kidney DiseaseSemantic proximity Read

Clinical findings, underlying pathogenetic processes and treatment of vascular dysfunction in autosomal dominant polycystic kidney disease.Semantic proximity Read

The genetics of vascular complications in autosomal dominant polycystic kidney disease (ADPKD).Semantic proximity Read

Novel PKD1 Mutation (c.G10086T) Drives High Intracranial Aneurysm Risk in Autosomal Dominant Polycystic Kidney Disease.Semantic proximity Read

PKD1-Associated Arachnoid Cysts in Autosomal Dominant Polycystic Kidney Disease.Semantic proximity Read

Genetic and environmental risk factors for intracranial aneurysm and subarachnoid haemorrhage among patients with Autosomal Dominant Polycystic Kidney DiseaseSemantic proximity Read

Should Patients with Autosomal Dominant Polycystic Kidney Disease Be Screened for Cerebral Aneurysms?Semantic proximity Read

Molecular pathogenesis of ADPKD: the polycystin complex gets complex.Semantic proximity Read

Vascular transcriptional and metabolic changes precede progressive intra-renal microvascular rarefaction in autosomal dominant polycystic kidney diseaseSemantic proximity Read

Identification of MMP1 as a novel risk factor for intracranial aneurysms in ADPKD using iPSC modelsSemantic proximity Read

Comprehensive bioinformatics analysis revealed potential key genes and pathways underlying abdominal aortic aneurysmSemantic proximity Read

Novel Pathways in the Pathobiology of Human Abdominal Aortic AneurysmsSemantic proximity Read