Article

<i>M. tuberculosis</i> microvariation is common and is associated with transmission: analysis of three years prospective universal sequencing in England

2019-06-24

Abstract excerpt

<h4>Background</h4> The prevalence, association with disease status, and public health impact of infection with mixtures of M. tuberculosis strains is unclear, in part due to limitations of existing methods for detecting mixed infections. <h4>Methods</h4> We developed an algorithm to identify mixtures of M. tuberculosis strains using next generation sequencing data, assessing performance using simulated seque...

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Literature Corpus work: 19af2bcf-74e2-5d1d-afb7-1702d58af42a
DOI: 10.1101/681502

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