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Malaria parasites utilize pyrophosphate to fuel an essential proton pump in the ring stage and the transition to trophozoite stage

2021-10-25

Abstract excerpt

The malaria parasite relies on anaerobic glycolysis for energy supply when growing inside RBCs as its mitochondrion does not produce ATP. The ring stage lasts ∼ 22 hours and is traditionally thought to be metabolically quiescent. However, recent studies show that the ring stage is active for several energy-costly processes including gene transcription/translation, protein export, and movement inside the RBC. It ha...

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Literature Corpus work
cdeeae37-de58-5056-a75c-609faf41d82d
DOI
10.1101/2021.10.25.465524
Open publication

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Malaria parasites utilize pyrophosphate to fuel an essential proton pump in the ring stage and the transition to trophozoite stageDOI 10.1101/2021.10.25.465524
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