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Analyzing Integrated Network of Methylation and Gene Expression Profiles in Lung Squamous Cell Carcinoma

2022-02-21

Abstract excerpt

Gene expression, DNA methylation, and their organizational relationships are commonly altered in lung squamous cell carcinoma (LUSC). To elucidate these complex interactions, we reconstructed a differentially expressed genes (DEGs) network and differentially methylated cytosine (DMCs) network by partial information decomposition and inverse correlation algorithm, respectively. Then, we performed graph union to int...

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Literature Corpus work
cdd6aa4a-5d08-5921-a1e3-994d02bd77c2
DOI
10.21203/rs.3.rs-1367606/v1
Open publication

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