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Article

Potential Genes Associated with the Survival of Lung Adenocarcinoma Were Identified by Methylation.

Computational and mathematical methods in medicine - 1 Jan 2020

Shen Ziyuan, He Chenlu, Chen Haimiao, Xiao Lishun, Jin Yingliang, Huang Shuiping

Abstract excerpt

BACKGROUND: Lung adenocarcinoma (LUAD) is the most common pathological type of lung cancer. The purpose of this study is to search for genes related to the prognosis of LUAD through methylation based on a linear mixed model (LMM). METHODS: Gene expression, methylation, and survival data of LUAD patients were downloaded from the TCGA database. Based on the LMM model, the GEMMA algorithm was used to screen the...

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PMID: 34007304
DOI: 10.1155/2020/7103412
PMCID: PMC8108640

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