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Article

Reconstruction of an integrated genome-scale co-expression network reveals key modules involved in lung adenocarcinoma.

PloS one - 1 Jan 2013

Bidkhori Gholamreza, Narimani Zahra, Hosseini Ashtiani Saman, Moeini Ali, Nowzari-Dalini Abbas, Masoudi-Nejad Ali

Abstract excerpt

Our goal of this study was to reconstruct a "genome-scale co-expression network" and find important modules in lung adenocarcinoma so that we could identify the genes involved in lung adenocarcinoma. We integrated gene mutation, GWAS, CGH, array-CGH and SNP array data in order to identify important genes and loci in genome-scale. Afterwards, on the basis of the identified genes a co-expression network was...

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PMID: 23874428
DOI: 10.1371/journal.pone.0067552
PMCID: PMC3708931

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