Article
A critical role of AREG for bleomycin-induced skin fibrosis
2021-01-20
Abstract excerpt
<title>Abstract</title> <p>We report our discovery of an important player in the development of skin fibrosis, a hallmark of scleroderma. Scleroderma is a fibrotic disease, affecting 70,000 to 150,000 Americans. Fibrosis is a pathological wound healing process that produces an excessive extracellular matrix to interfere with normal organ function. Fibrosis contributes to nearly half of human mortality. Scleroderm...
Topics
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- Cancer-related molecular mechanisms research
- Connective Tissue Growth Factor Research
- Dermatologic Treatments and Research
- Extracellular vesicles in disease
- Skin and Cellular Biology Research
- Systemic Sclerosis and Related Diseases
- Wnt/β-catenin signaling in development and cancer
- Wound Healing and Treatments
Identifiers and source
- Literature Corpus work
- cd6bea46-3d92-5aa3-bde2-f19465b0cf0d
- DOI
- 10.21203/rs.3.rs-150012/v1
