Back to search

Article

Genetic characterization of stem cell-like cancer cell in the peri-tumoral regions and proliferative lymphocyte in the peripheral blood of patients with glioblastoma

2020-01-07

Abstract excerpt

The glioblastoma (GBM) recurrence rate is high, despite multimodal treatment including surgery, radiotherapy, chemotherapy, and immunotherapy. Most recurrences occur at the resection margin that is located outside the GBM contrast-enhancing region (C region) of magnetic resonance imaging. However, the nature of the GBM cells that lie outside the C region is unclear. We used single-cell RNA sequencing (scRNA-seq) t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
cd5a92a8-a8fd-57fc-90bb-4a4346619394
DOI
10.1101/2020.01.06.895987
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genetic characterization of stem cell-like cancer cell in the peri-tumoral regions and proliferative lymphocyte in the peripheral blood of patients with glioblastomaDOI 10.1101/2020.01.06.895987
Understanding the Genomic Landscape of Glioblastoma: Opportunities for Targeted TherapiesSemantic proximity
High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastomaSemantic proximity
Tumor Heterogeneity and Molecular Characteristics of Glioblastoma Revealed by Single-Cell RNA-Seq Data AnalysisSemantic proximity
Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human GlioblastomaSemantic proximity
Characterizing the Genomic Profile in High-Grade Gliomas: From Tumor Core to Peritumoral Brain Zone, Passing through Glioma-Derived TumorspheresSemantic proximity
Unveiling novel cell clusters and biomarkers in glioblastoma and its peritumoral microenvironment at the single-cell perspectiveSemantic proximity
Molecular Pathways and Genomic Landscape of Glioblastoma Stem Cells: Opportunities for Targeted TherapySemantic proximity
Single-Cell RNAseq analysis of infiltrating neoplastic cells at the migrating front of human glioblastomaSemantic proximity
Glioblastoma scRNA-seq shows treatment-induced, immune-dependent increase in mesenchymal cancer cells and structural variants in distal neural stem cellsSemantic proximity
Single-cell molecular characterization to partition the human glioblastoma tumor microenvironment (TME) genetic backgroundSemantic proximity
Single-Cell RNA-Sequencing Shift in the Interaction Pattern Between Glioma Stem Cells and Immune Cells During TumorigenesisSemantic proximity
Integration of single-cell RNA sequencing and spatial transcriptomics to reveal the glioblastoma heterogeneitySemantic proximity
Select a neighboring publication to make it the new centre.