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A first-principles geometric model for dynamics of motor-driven centrosomal asters

2024-06-21

Abstract excerpt

The centrosomal aster is a mobile and adaptable cellular organelle that exerts and transmits forces necessary for tasks such as nuclear migration and spindle positioning. Recent experimental and theoretical studies of nematode and human cells demonstrate that pulling forces on asters by cortically anchored force generators are dominant during such processes. Here we present a comprehensive investigation of a first...

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Literature Corpus work
cd5132b3-c906-5641-bbdd-a8cdf0e1a01c
DOI
10.1101/2024.06.20.599849
Open publication

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A first-principles geometric model for dynamics of motor-driven centrosomal astersDOI 10.1101/2024.06.20.599849
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