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Article

Microtubule-Based Mechanisms of Pronuclear Positioning

23 Feb 2020

Abstract excerpt

The zygote is defined as a diploid cell resulting from the fusion of two haploid gametes. Union of haploid male and female pronuclei in many animals occurs through rearrangements of the microtubule cytoskeleton into a radial array of microtubules known as the sperm aster. The sperm aster nucleates from paternally-derived centrioles attached to the male pronucleus after fertilization. Nematode, echinoderm, and...

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PMID: 32102180
DOI: 10.3390/cells9020505

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