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Article

PCNA-associated factor (KIAA0101/PCLAF) overexpression and gene copy number alterations in hepatocellular carcinoma tissues

2020-12-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> PCNA-associated factor, the protein encoded by the KIAA0101/PCLAF gene, is a cell-cycle regulated oncoprotein that regulates DNA synthesis, maintenance of DNA methylation, and DNA-damage bypass, through the interaction with the human sliding clamp PCNA. KIAA0101/PCLAF is overexpressed in various cancers, including hepatocellular carcinoma (HCC). However, it rema...

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Identifiers and source

Literature Corpus work
cd396978-77d0-55d3-8f59-fd2e73bbeeb2
DOI
10.21203/rs.3.rs-39782/v2
Open publication

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PCNA-associated factor (KIAA0101/PCLAF) overexpression and gene copy number alterations in hepatocellular carcinoma tissuesDOI 10.21203/rs.3.rs-39782/v2
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