Article

Dirichlet-multinomial modelling outperforms alternatives for analysis of microbiome and other ecological count data

2019-07-22

Abstract excerpt

Molecular ecology regularly requires the analysis of count data that reflect the relative abundance of features of a composition (e.g., taxa in a community, gene transcripts in a tissue). The sampling process that generates these data can be modeled using the multinomial distribution. Replicate multinomial samples inform the relative abundances of features in an underlying Dirichlet distribution. These distributio...

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Literature Corpus work: cd1f6414-3d57-5b80-b8b9-a272a89d64ee
DOI: 10.1101/711317

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