Back to search

Article

DeepBioSim: Efficient and Versatile Methods for Microbiome Data Simulation with Minimal Statistical Assumptions

2025-08-26

Abstract excerpt

<h4>Background</h4> The human microbiome profoundly influences health and disease. Robust computational and statistical tools for identifying causal microbe–disease links are therefore critical to uncovering the mechanistic basis of these associations. Yet benchmarking such tools remains difficult: microbiome datasets are sparse, high-dimensional, and contain complex dependencies, and no gold-standard reference s...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
0c11e5e2-5a6e-533b-8986-cd824317cce2
DOI
10.1101/2025.08.21.670443
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
DeepBioSim: Efficient and Versatile Methods for Microbiome Data Simulation with Minimal Statistical AssumptionsDOI 10.1101/2025.08.21.670443
A Statistical Model for Describing and Simulating Microbial Community ProfilesSemantic proximity
Predicting microbiome compositions from species assemblages through deep learningSemantic proximity
Microbial dynamics inference at ecosystem-scaleSemantic proximity
MDITRE: scalable and interpretable machine learning for predicting host status from temporal microbiome dynamicsSemantic proximity
Deep Learning Enables Design of Multifunctional Synthetic Human Gut Microbiome DynamicsSemantic proximity
MIDASim: a fast and simple simulator for realistic microbiome dataSemantic proximity
The MTIST platform: a microbiome time series inference standardized test simulation, dataset, and scoring systemsSemantic proximity
The MTIST platform: a microbiome time series inference standardized testSemantic proximity
SimMiL: Simulating Microbiome Longitudinal DataSemantic proximity
BEEM-Static: Accurate inference of ecological interactions from cross-sectional metagenomic dataSemantic proximity
The Second Brain: Diffusion Models for Realistic Human Microbiome GenerationSemantic proximity
A realistic benchmark for the identification of differentially abundant taxa in (confounded) human microbiome studiesSemantic proximity
Select a neighboring publication to make it the new centre.