Article

DirtyGenes: significance testing for gene or bacterial population composition changes using the Dirichlet distribution

2017-10-16

Abstract excerpt

High throughput sequencing, and quantitative polymerase chain reaction (qPCR), can detect changes in bacterial communities or the genes that they carry, between different environments or treatments. These methods are applied widely to microbiomes in humans, animals, soil and water; an important application is for changes in antimicrobial resistance genes (ARGs). However, at present, there is no statistical method...

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Literature Corpus work: 70211626-fd17-57be-8d19-d3774b827d3a
DOI: 10.1101/204321

Open publication

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