Article

Interventions with Potential to Mitigate Injection Site Reactions Following Subcutaneous Elamipretide Administration: A Phase 1, Crossover Study

2023-07-12

Abstract excerpt

<h4>Aim: </h4> Elamipretide is a mitochondrial-targeting agent being developed for the treatment of mitochondrial dysfunction-associated diseases. While prior studies have shown that subcutaneous elamipretide is generally safe/well tolerated, injection site reactions (ISRs) were reported in most subjects. We evaluated the efficacy of interventions to mitigate ISRs, identify underlying ISR mechanisms, and evaluate...

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Literature Corpus work: ccf2d249-8c69-522e-b21e-87ee6e6a992a
DOI: 10.22541/au.168913984.48436087/v1

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