Article

Interventions with Potential to Mitigate Injection Site Reactions Following Subcutaneous Elamipretide Administration: A Phase 1, Crossover Study

2023-04-06

Abstract excerpt

<h4>Background: </h4> and Purpose: Elamipretide is a mitochondrial-targeting agent being developed for the treatment of mitochondrial dysfunction-associated diseases. While prior studies have shown that subcutaneous elamipretide is generally safe/well tolerated, injection site reactions (ISRs) were reported in most subjects. We evaluated the efficacy of interventions to mitigate ISRs, identify underlying ISR mecha...

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Literature Corpus work: 60bd9265-9459-54f0-9e19-c521c48b820a
DOI: 10.22541/au.168075727.77826241/v1

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