Article
Management of adverse reactions to biologic agents.
Allergy and asthma proceedings - 1 Nov 2017
Isabwe Ghislaine Annie C, de Las Vecillas Sanchez Leticia, Castells Mariana
Abstract excerpt
Hypersensitivity reactions (HSR) to targeted biologic agents present as immediate reactions during infusion or as delayed reactions (after one or more exposures). The new classification includes phenotypes, endotypes, and biomarkers. Phenotypes include immediate type I (immunoglobulin E [IgE] or non-IgE mediated), cytokine release, mixed (type I/cytokine), and immune complexes type III (IgG mediated) reactions as...
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