Article
Parthenolide inhibits proliferation of Kaposi's sarcoma-associated herpesvirus infected cells by suppression of the NF-κB signaling pathway
2022-05-19
Abstract excerpt
<title>Abstract</title> <p>The disease caused by Kaposi's sarcoma-associated herpesvirus (KSHV) is one of the major reasons for the death in AIDS. Development of anti-KSHV drugs is thus crucial. This study is to investigate the effect of Parthenolide (PTL) on the proliferation and NF-κB signaling pathway of KSHV-infected cells. iSLK.219 and KSHV infected SH-SY5Y cells (SK-RG) were treated with PTL. Taq-Man real-t...
Topics
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- Cytomegalovirus and herpesvirus research
- Herpesvirus Infections and Treatments
- Histiocytic Disorders and Treatments
- HIV/AIDS drug development and treatment
- Immune Cell Function and Interaction
- Parvovirus B19 Infection Studies
- Pharmacological Effects of Natural Compounds
- Viral-associated cancers and disorders
Identifiers and source
- Literature Corpus work
- cc080c9a-adff-5812-8aa9-c0bc159ec5c5
- DOI
- 10.21203/rs.3.rs-1577196/v1
