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Article

Regulation of growth signalling and cell cycle by Kaposi's sarcoma‐associated herpesvirus genes

24 Nov 2004

Abstract excerpt

Kaposi's sarcoma-associated herpesvirus (KSHV) is the primary aetiological agent of at least three malignancies associated with HIV infection and immunosuppression: Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease. KSHV encodes proteins that deregulate key checkpoints in the signalling pathways governing cell proliferation, which may ultimately contribute to the virus' oncogenic...

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PMID: 15566428
DOI: 10.1111/j.0959-9673.2004.00407.x

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