Article
Gaudichaudione H inhibits Herpes Simplex Virus-1 replication by regulating cellular nuclear factor-κB in an interferon-γ-inde-pendent manner
2023-01-07
Abstract excerpt
The highly prevalent herpes simplex virus type 1 (HSV-1) causes keratoconjunctivitis and encephalitis. Viral DNA polymerase-inhibiting nucleoside analogs (such as acyclovir) are standard treatment agents against HSV infections but are limited by severe drug resistance issues. Thus, new antiviral agents with novel targets are urgently needed. Earlier, we investigated the anti-cancer, anti-inflammatory, and antibact...
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Identifiers and source
- Literature Corpus work
- 3e9cb27c-f318-55ef-b19c-a1b6c8bc3d9b
- DOI
- 10.1101/2023.01.06.523065
