Article

Palliative chemotherapy is well tolerated in a patient with metastatic colorectal cancer due to Bloom syndrome with a novel BLM mutation

2025-02-19

Abstract excerpt

Bloom syndrome is an autosomal recessive condition of genomic instability caused by increased sister-chromatid exchange, which results in a predisposition to a variety of cancers at a young age. The early ages of these cancers, as well as the nature of Bloom syndrome itself, alter the expected response to and toxicities of chemotherapy in patients with this condition. We report a 16-year-old patient with undiagnos...

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Literature Corpus work: cbe94aae-c889-55bb-bc97-1c2baa1ded16
DOI: 10.22541/au.173994139.99044724/v1

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