Article

TXTL-Powered K1F Internal Capsid Protein Engineering for Specific, Orthogonal and Rapid Phage-based Pathogen Detection

2024-05-06

Abstract excerpt

The internal capsid proteins that reside within phage of the Podoviridae family hold high potential for being used as sensitive and reliable diagnostic tools. The concealed nature of the capsid interior ensures that any encapsulated signal or signal generating enzyme, e.g., fused to an internal capsid protein, is suppressed whilst the phage is unaccompanied by its host. Furthermore, the only naturally occurring me...

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Literature Corpus work: cbbc15ea-6f80-5406-b6ae-c97dda649fa1
DOI: 10.1101/2024.05.06.592667

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