Back to search

Article

Pan-Cancer Analysis and Validation of NT5DC2: Emphasizing Its Prognostic Significance and Immunological Role in TNBC

2025-03-31

Abstract excerpt

<title>Abstract</title> <p>Background 5′-Nucleotidase Domain Containing 2 (NT5DC2), a cNT5-II family member catalyzing nucleotide hydrolysis, plays a crucial role in tumor initiation and progression. This study aims to elucidate NT5DC2’s potential role in multiple cancers and confirm its oncogenic significance in triple-negative breast cancer (TNBC). Methods Multiple databases analyzed NT5DC2 expression pattern...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
cbbb05dc-b5c0-5476-93c6-3a6047bc74b2
DOI
10.21203/rs.3.rs-6212403/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Pan-Cancer Analysis and Validation of NT5DC2: Emphasizing Its Prognostic Significance and Immunological Role in TNBCDOI 10.21203/rs.3.rs-6212403/v1
BIRC5 as a Potential Biomarker and Therapeutic Target for Lung Adenocarcinoma: A Comprehensive Bioinformatics AnalysisSemantic proximity
CCR5 is a prognostic biomarker and an immune regulator for triple negative breast cancerSemantic proximity
A Retrospective View on Triple Negative Breast Cancer Microenvironment: Novel Markers, Interactions, and Mechanisms of Tumor-Associated Components using public Single-cell RNA Seq DatasetsSemantic proximity
Computational Identification of ECT2 as a Potential Pan-Cancer Biomarker and Therapeutic Target Through Integrated Genomic Data AnalysisSemantic proximity
Pan-cancer analysis identifies NT5E as a novel prognostic biomarker on cancer-associated fibroblasts associated with unique tumor microenvironmentSemantic proximity
HDHD5 promotes triple-negative breast cancer growth and drives EMT-associated phenotypes via regulating S100A4.Semantic proximity
BIRC5 expression correlated with immunosuppressive phenotype and predicted inferior response to immunotherapy in lung adenocarcinomaSemantic proximity
The role of CCT5 in human tumors: a pan-cancer analysisSemantic proximity
DOCK2 is a Biomarker for Predicting the Prognosis of Lung Adenocarcinoma and Associated with Immune InfiltrationSemantic proximity
Molecular subtyping and functional validation of TTK, TPX2, UBE2C, and LRP8 in sensitivity of TNBC to paclitaxelSemantic proximity
Comprehensive pan-cancer analysis reveals NTN1 as an Immune infiltrate risk factor and its potential prognostic value in SKCMSemantic proximity
A comprehensive investigation of crosstalk between m5C writer NSUN2 and MYC in breast cancer microenvironmentSemantic proximity
Select a neighboring publication to make it the new centre.