Article

Estimating malaria antigen dynamics and the time to negativity of next-generation malaria rapid diagnostic tests

2025-01-14

Abstract excerpt

<h4>Background</h4> Rapid diagnostic tests (RDTs) used to diagnose Plasmodium falciparum (Pf) predominantly target the antigen Histidine Rich Protein 2 (HRP2) exclusively. With the emergence of hrp2/hrp3 gene deletions, RDTs targeting other antigens such as the essential enzyme Lactate Dehydrogenase (LDH) are needed. The dynamics of LDH relative to HRP2 are currently not well described but are needed to inform...

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Literature Corpus work: cbb04ded-8369-560a-8fcc-4ede82434343
DOI: 10.1101/2025.01.13.25320483

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