Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of false-negative rapid diagnostic tests for symptomatic malaria in the Democratic Republic of the Congo

22 Mar 2021

Abstract excerpt

The majority of Plasmodium falciparum malaria diagnoses in Africa are made using rapid diagnostic tests (RDTs) that detect histidine-rich protein 2. Increasing reports of false-negative RDT results due to parasites with deletions of the pfhrp2 and/or pfhrp3 genes (pfhrp2/3) raise concern about existing malaria diagnostic strategies. We previously identified pfhrp2-negative parasites among asymptomatic children in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement system in diseases
Share to Malaria Research and Control
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33753817
DOI: 10.1038/s41598-021-85913-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of false-negative rapid diagnostic tests for symptomatic malaria in the Democratic Republic of the CongoPMID 33753817Read ↗

Causes of false-negative rapid diagnostic tests for symptomatic malaria in the DRCSemantic proximity Read ↗

Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions among patients in the DRC enrolled from 2017 to 2018Semantic proximity Read ↗

Deletions of pfhrp2 and pfhrp3 genes were uncommon in rapid diagnostic test-negative Plasmodium falciparum isolates from UgandaSemantic proximity Read ↗

Evaluating Malaria Rapid Diagnostic Tests and Microscopy for Detecting Plasmodium Infection and Status of Plasmodium falciparum Histidine-Rich Protein 2/3 Gene Deletions in Southeastern NigeriaSemantic proximity Read ↗

Low prevalence of Plasmodium falciparum parasites lacking pfhrp2/3 genes among asymptomatic and symptomatic school-age children in Kinshasa, Democratic Republic of CongoSemantic proximity Read ↗

PfHRP2-PfHRP3 diversity among Kenyan isolates and comparative evaluation of PfHRP2/pLDH malaria RDT with microscopy and nested PCR methodologies.Semantic proximity Read ↗

Deletions of the Plasmodium falciparum pfhrp2 and pfhrp3 genes among patients enrolled at six locations in the DRC: 2017–2018Semantic proximity Read ↗

Streamlined, PCR-based testing for pfhrp2- and pfhrp3-negative Plasmodium falciparumSemantic proximity Read ↗

Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South SudanSemantic proximity Read ↗

Community-based surveys for Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions in selected regions of mainland TanzaniaSemantic proximity Read ↗

A novel multiplex qPCR assay for detection of Plasmodium falciparum with histidine-rich protein 2 and 3 (pfhrp2 and pfhrp3) deletions in polyclonal infectionsSemantic proximity Read ↗

<i>Plasmodium falciparum w</i>ith<i>pfhrp2/3</i>deletion not detected in a 2018-2021 malaria longitudinal cohort study in Kinshasa Province, Democratic Republic of the CongoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.