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Article

Characterization of the Temporal Profile of the Antinociceptive Effects of an Intravenous Bolus of Ketamine Using the Analgesia Nociception Index

2024-10-21

Abstract excerpt

<title>Abstract</title> <p>Purpose An effect-site target-controlled infusion (TCI) would allow a more precise titration of intravenous analgesics effect. The analgesia nociception index (ANI) continuously monitors the analgesia/nociception balance during general anesthesia. This study aims to derive a PKPD model of ketamine to allow an effect-site TCI administration using the ANI information and previously descr...

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Literature Corpus work
cba170f9-99b9-50c6-b0a2-324cbeda6d40
DOI
10.21203/rs.3.rs-5027055/v1
Open publication

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