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Determination of the EC90 of remifentanil for blocking the adrenergic responses to intubation when administered with propofol: an up-down sequential allocation study protocol using the k-in-a-row design versus biased-coin design

2025-03-31

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Endotracheal intubation(EI), as a noxious stimulus, can cause significant adrenergic responses. Remifentanil and propofol have excellent controllable pharmacokinetic characteristics and are commonly used in anesthesia induction. It is vital to assess how drug effects change with increasing doses using dose-response characterisation in anesthesia induction. It has...

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Literature Corpus work
e0a33372-93f1-5497-a12f-431bdef624fb
DOI
10.21203/rs.3.rs-5192866/v1
Open publication

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Determination of the EC90 of remifentanil for blocking the adrenergic responses to intubation when administered with propofol: an up-down sequential allocation study protocol using the k-in-a-row design versus biased-coin designDOI 10.21203/rs.3.rs-5192866/v1
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