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Combining ropivacaine transversus abdominis plane block with intravenous lidocaine infusion in adults undergoing colorectal cancer surgery: an open-label, dose-escalation exploratory trial

2025-03-27

Abstract excerpt

<title>Abstract</title> <p>Background The concurrent use of a ropivacaine transversus abdominis plane (TAP) block with intravenous lidocaine infusion, though effective for pain relief, raises safety concerns regarding local anesthetic systemic toxicity (LAST). This study aimed to assess the dose-risk relationship of LAST in this combination by escalating the ropivacaine dose while fixing the lidocaine dose. Meth...

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Literature Corpus work
756ed741-ace0-5bba-895a-d950ffc43fe4
DOI
10.21203/rs.3.rs-5690114/v1
Open publication

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Combining ropivacaine transversus abdominis plane block with intravenous lidocaine infusion in adults undergoing colorectal cancer surgery: an open-label, dose-escalation exploratory trialDOI 10.21203/rs.3.rs-5690114/v1
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