Seoul orthohantavirus evades innate immune activation by reservoir endothelial cells

Abstract excerpt

Pathogenic hantaviruses are maintained world-wide within wild, asymptomatic rodent reservoir hosts, with increasingly frequent human spillover infections resulting in severe hemorrhagic fever disease. With no approved therapeutics or vaccines, research has, until recently, focused on understanding the drivers of immune-mediated pathogenesis. An emerging body of work is now investigating the mechanisms that allow f...

Topics

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• Animal Virus Infections Studies
• Cancer-related molecular mechanisms research
• interferon and immune responses
• Mosquito-borne diseases and control
• Vector-Borne Animal Diseases
• Viral gastroenteritis research and epidemiology
• Viral Infections and Outbreaks Research
• Viral Infections and Vectors

Identifiers and source

Literature Corpus work

cb517e3b-4cb1-54a4-9f62-42c2e535946b

DOI

10.1101/2024.06.18.599607