Article

Copy number variation heterogeneity reveals biological inconsistency in hierarchical cancer classifications

2024-09-25

Abstract excerpt

<title>Abstract</title> <p>Cancers are heterogeneous diseases with unifying features of abnormal and consuming cell growth, where the deregulation of normal cellular functions is initiated by the accumulation of genomic mutations in cells of - potentially - any organ. At diagnosis malignancies typically present with patterns of somatic genome variants on diverse levels of heterogeneity. Among the different types...

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Literature Corpus work: cb479a63-b5c3-59d2-bd52-c51d70a1662c
DOI: 10.21203/rs.3.rs-4964097/v1

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