Article

The impact of pubertal stress and adult hormone exposure on the transcriptome of the developing hypothalamus

2023-10-05

Abstract excerpt

Why individuals suffer negative consequences following stress is a complex phenomenon that is dictated by individual factors, the timing of stress within the lifespan, and when in the lifespan the consequences are measured. Women who undergo adverse childhood experiences are at risk for lasting biological consequences, including affective and stress dysregulation. We have shown that pubertal adversity is associate...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cb3cf987-fb81-5e1a-bf22-179d0fd5ff9a
DOI: 10.1101/2023.10.03.559350

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The impact of pubertal stress and adult hormone exposure on the transcriptome of the developing hypothalamusDOI 10.1101/2023.10.03.559350Read

Stress during puberty and adulthood pregnancy impact histone acetylation regulators in the hypothalamusSemantic proximity Read

Prenatal programming of stress responsiveness and behaviours: Progress and perspectivesSemantic proximity Read

Maternal influences on epigenetic programming of the developing hypothalamic‐pituitary‐adrenal axisSemantic proximity Read

Emerging Genetic and Epigenetic Mechanisms Underlying Pubertal Maturation in AdolescenceSemantic proximity Read

Examining the Intersection of Sex and Stress in Modelling Neuropsychiatric DisordersSemantic proximity Read

Early programming of reproductive health and fertility: novel neuroendocrine mechanisms and implications in reproductive medicineSemantic proximity Read

Early life stress induces social behavioral deficits and peripheral biomarker alterations in adolescence that perpetuate intergenerationallySemantic proximity Read

Transgenerational inheritance of chronic adolescent stress: Effects of stress response and the amygdala transcriptome.Semantic proximity Read

Developmental programming of the HPA axis and related behaviours: epigenetic mechanismsSemantic proximity Read

Subregion-Specific Transcriptomic Profiling of Rat Brain Reveals Sex-Distinct Gene Expression Impacted by Adolescent StressSemantic proximity Read

Glucocorticoid effects on the brain: from adaptive developmental plasticity to allostatic overloadSemantic proximity Read

Role of the hypothalamic–pituitary–adrenal axis in developmental programming of health and diseaseSemantic proximity Read