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Article

Developmental programming of the HPA axis and related behaviours: epigenetic mechanisms

4 Apr 2019

Abstract excerpt

It has been approximately 30 years since the seminal discoveries of David Barker and his colleagues, and research is beginning to unravel the mechanisms that underlie developmental programming. The early environment of the embryo, foetus and newborn have been clearly linked to altered hypothalamic-pituitary-adrenal (HPA) function and related behaviours through the juvenile period and into adulthood. A number of...

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PMID: 30917340
DOI: 10.1530/joe-19-0057

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