Article
Transgenerational inheritance of chronic adolescent stress: Effects of stress response and the amygdala transcriptome.
Genes, brain, and behavior - 1 Sept 2019
Manners M T, Yohn N L, Lahens N F, Grant G R, Bartolomei M S, Blendy J A
Abstract excerpt
Adolescent stress can impact health and well-being not only during adulthood of the exposed individual but even in future generations. To investigate the molecular mechanisms underlying these long-term effects, we exposed adolescent males to stress and measured anxiety behaviors and gene expression in the amygdala-a critical region in the control of emotional states-in their progeny for two generations, offspring...
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