Article

Dynamic expression of smRNA from fecal exosome in disease progression of an inflammatory bowel disorder mouse model

2021-02-25

Abstract excerpt

<h4>ABSTRACT</h4> Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract affecting over 3 million adults in the United States. Despite being widespread, reliable early diagnostic tests are not available. We examined exosomal small RNA (smRNA), specifically targeting microRNA (miRNA) and piRNA from the stool samples of IBD model mice, interleukin 10 knockout mice (IL-10 K...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cb15f6f7-0491-580a-b96a-b23e13a88687
DOI: 10.1101/2021.02.24.432648

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dynamic expression of smRNA from fecal exosome in disease progression of an inflammatory bowel disorder mouse modelDOI 10.1101/2021.02.24.432648Read

MicroRNA‐microbiota interactions: Emerging strategies for modulating intestinal homeostasis and enhancing host healthSemantic proximity Read

Gut Microbial Impact on Colitis and Colitis-Associated Carcinogenesis in a Primary Sclerosing Cholangitis-IBD ModelSemantic proximity Read

Transcriptome profiling of ulcerative colitis mouse model suggests biomarkers and therapeutic targets for human colitisSemantic proximity Read

Importance of Fecal Microbiota Transplantation and Molecular Regulation as Therapeutic Strategies in Inflammatory Bowel DiseasesSemantic proximity Read

High-Resolution Gene Expression Profiling Using RNA Sequencing in Patients With Inflammatory Bowel Disease and in Mouse Models of ColitisSemantic proximity Read

Exosomes as a New Delivery Vehicle in Inflammatory Bowel DiseaseSemantic proximity Read

Harnessing murine models of Crohn's disease ileitis to advance concepts of pathophysiology and treatment.Semantic proximity Read

DSS Colitis Model: Traps, Tricks, and Reporting RecommendationsSemantic proximity Read

Emerging Involvement of long non-coding RNAs in gastrointestinal associated inflammatory disorders.Semantic proximity Read

The role of miRNA in IBS pathogenesis, diagnosis and therapy: The latest thoughtSemantic proximity Read

Macrophage-derived microRNA-223 Promotes Intestinal Mucosal Barrier Dysfunction via Exosomal Pathways in Inflammatory Bowel DiseaseSemantic proximity Read

The non-invasive exfoliated transcriptome (exfoliome) reflects the tissue-level transcriptome in a mouse model of NSAID enteropathySemantic proximity Read