Article

Health Impact Assessment of BRCA1/2 Cascade Screening for the Personalized Prevention of Hereditary Breast and Ovarian Cancers in Italy

2026-04-15

Abstract excerpt

<h4>Introduction</h4> Pathogenic germline variants in the BRCA1 and BRCA2 genes confer a markedly increased risk of breast and ovarian cancer, for which effective preventive strategies are available. Although national and international guidelines recommend BRCA testing and cascade screening of relatives, implementation in Italy remains highly heterogeneous across regions. This study estimates the potential pop...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cad51eb6-6ade-58f1-8ccf-d92100cb16bb
DOI: 10.64898/2026.04.13.26350758

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Health Impact Assessment of BRCA1/2 Cascade Screening for the Personalized Prevention of Hereditary Breast and Ovarian Cancers in ItalyDOI 10.64898/2026.04.13.26350758Read

Cascade testing in Italian Hereditary Breast Ovarian Cancer families: a missed opportunity for cancer prevention?Semantic proximity Read

Uptake of Cascade Genetic Testing for Hereditary Breast Cancer in the Public Health System in a Middle-Income Country: A Real-World Study.Semantic proximity Read

Implementing rapid, robust, cost-effective, patient-centred, routine genetic testing in ovarian cancer patientsSemantic proximity Read

Cascade testing as the missing link in cancer prevention among Lynch syndrome families.Semantic proximity Read

Cancer Predisposition Cascade Screening for Hereditary Breast/Ovarian Cancer and Lynch Syndromes in Switzerland: Study ProtocolSemantic proximity Read

A regional population-based hereditary breast cancer screening tool in Italy: First 5-year results.Semantic proximity Read

Uptake of cancer risk management strategies among women who undergo cascade genetic testing for breast cancer susceptibility genes.Semantic proximity Read

Genetic testing and economic evaluations: a systematic review of the literature.Semantic proximity Read

Cost-Effectiveness of BRCA 1/2 Genetic Test and Preventive Strategies: Using Real-World Data From an Upper-Middle Income CountrySemantic proximity Read

A Multi-Level Analysis of Barriers and Promoting Factors to Cascade Screening Uptake Among Male Relatives of BRCA1/2 Carriers: A Qualitative Study.Semantic proximity Read

Delivery Of Cascade Screening For Hereditary Conditions: A Scoping Review Of The Literature.Semantic proximity Read