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Uptake of cancer risk management strategies among women who undergo cascade genetic testing for breast cancer susceptibility genes.

Cancer - 1 Oct 2021

Makhnoon Sukh, Tran Grace, Levin Brooke, Mattie Kristin D, Dreyer Brian, Volk Robert J, Grana Generosa, Arun Banu K, Peterson Susan K

Abstract excerpt

BACKGROUND: Uptake of cancer risk management based on inherited predispositions, which encompasses bilateral mastectomy (BLM), bilateral salpingo-oophorectomy (BSO), and intensified screening, is the primary motivation for cascade testing for hereditary breast and ovarian cancer (HBOC). However, long-term outcome data for cascade testers are lacking. METHODS: Medical records were abstracted for all unaffected...

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Identifiers

PMID: 34157779
DOI: 10.1002/cncr.33668
PMCID: PMC8685932

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