Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Multi-Level Analysis of Barriers and Promoting Factors to Cascade Screening Uptake Among Male Relatives of BRCA1/2 Carriers: A Qualitative Study.

Psycho-oncology - 1 May 2025

Ongaro G, Hamilton J G, Groner V, Hay J L, Calvello M, Oliveri S, Bonanni B, Feroce I, Pravettoni G

Abstract excerpt

BACKGROUND: Pathogenic variants in the BRCA1/2 genes significantly elevate risks of breast, ovarian, prostate, and pancreatic cancer. Clinical guidelines recommend cascade screening (CS) to identify at-risk family members and advance genetically targeted disease prevention. However, despite the benefits of CS, testing uptake remains suboptimal, particularly among male first-degree relatives (FDRs) of female...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein
Share to BRCA2 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Early Detection of Cancer

Share to Genes, BRCA1

Share to Genes, BRCA2

Share to Health Knowledge, Attitudes, Practice

Share to Patient Acceptance of Health Care

Share to Qualitative Research

Source

Open in PubMed Open full text

Identifiers

PMID: 40374330
DOI: 10.1002/pon.70160
PMCID: PMC12081208

Genes

CS
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Multi-Level Analysis of Barriers and Promoting Factors to Cascade Screening Uptake Among Male Relatives of BRCA1/2 Carriers: A Qualitative Study.PMID 40374330Read ↗

Psychosocial barriers and facilitators for cascade genetic testing in hereditary breast and ovarian cancer: a scoping review.Semantic proximity Read ↗

Can Family Motivation Enhance Men's Uptake of Cascade Screening for Familial BRCA1/2 Mutations?Semantic proximity Read ↗

Streamlined Genetic Education and Cascade Testing in Men from Hereditary Breast Ovarian Cancer Families: A Randomized Trial.Semantic proximity Read ↗

Stakeholder Perspectives on Overcoming Barriers to Cascade Testing in Lynch Syndrome: A Qualitative StudySemantic proximity Read ↗

Cascade genetic testing for hereditary cancer syndromes: a review of barriers and breakthroughs.Semantic proximity Read ↗

Barriers to completion of cascade genetic testing: how can we improve the uptake of testing for hereditary breast and ovarian cancer syndrome?Semantic proximity Read ↗

Timely targeted testing for hereditary cancer syndromes - Importance of clinician-facilitated cascade testing in the first year post-diagnosis.Semantic proximity Read ↗

Cascade testing as the missing link in cancer prevention among Lynch syndrome families.Semantic proximity Read ↗

Challenges and opportunities for Lynch syndrome cascade testing in the United States.Semantic proximity Read ↗

Obstacles in genetic testing for germline BRCA1/2 pathogenic mutations in patients with primary breast and ovarian cancer in Switzerland.Semantic proximity Read ↗

Exploration of familial genetic test result communication among Black women within an academic safety net hospital.Semantic proximity Read ↗

Delivery Of Cascade Screening For Hereditary Conditions: A Scoping Review Of The Literature.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.