Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cascade testing in Italian Hereditary Breast Ovarian Cancer families: a missed opportunity for cancer prevention?

Familial cancer - 1 Jun 2024

Trevisan Lucia, Godino Lea, Battistuzzi Linda, Innella Giovanni, Luppi Elena, Buzzatti Giulia, Gismondi Viviana, Blondeaux Eva, Bonelli Luigina Ada, Turchetti Daniela, Varesco Liliana

Abstract excerpt

Healthy carriers of BRCA1/2 pathogenic variants (PVs) may benefit from risk-reducing measures of proven efficacy. The main approach to identify these individuals is cascade testing, and strategies to support this complex process are under investigation. In Italy, cascade testing has received little attention; therefore, we analyzed the uptake and characteristics of BRCA1/2 cascade testing in families diagnosed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to BRCA1 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRCA2 Protein

Share to Breast Neoplasms

Share to Genetic Testing

Share to Hereditary Breast and Ovarian Cancer Syndrome

Share to Ovarian Neoplasms

Source

Identifiers

PMID: 37968543
DOI: 10.1007/s10689-023-00349-w

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cascade testing in Italian Hereditary Breast Ovarian Cancer families: a missed opportunity for cancer prevention?PMID 37968543Read ↗

Cascade testing in Italian Hereditary Breast Ovarian Cancer families: a missed opportunity for cancer prevention?Semantic proximity Read ↗

Uptake of Cascade Genetic Testing for Hereditary Breast Cancer in the Public Health System in a Middle-Income Country: A Real-World Study.Semantic proximity Read ↗

Cascade testing as the missing link in cancer prevention among Lynch syndrome families.Semantic proximity Read ↗

Cancer genetic counselling for hereditary breast cancer in the era of precision oncology.Semantic proximity Read ↗

Uptake of cancer risk management strategies among women who undergo cascade genetic testing for breast cancer susceptibility genes.Semantic proximity Read ↗

Relatives from Hereditary Breast and Ovarian Cancer and Lynch Syndrome Families Forgoing Genetic Testing: Findings from the Swiss CASCADE CohortSemantic proximity Read ↗

The TESTBREAST journey: Revisiting the importance of early detection by frequent screening of women at high risk of breast cancer.Semantic proximity Read ↗

Cascade genetic testing: an underutilized pathway to equitable cancer care?Semantic proximity Read ↗

BRCA1 and BRCA2 genetic testing in Italian breast and/or ovarian cancer families: mutation spectrum and prevalence and analysis of mutation prediction modelsSemantic proximity Read ↗

Only 32.3% of Breast Cancer Families with Pathogenic Variants in Cancer Genes Utilized Cascade Genetic TestingSemantic proximity Read ↗

Health Impact Assessment of BRCA1/2 Cascade Screening for the Personalized Prevention of Hereditary Breast and Ovarian Cancers in ItalySemantic proximity Read ↗

Index case identification and outcomes of cascade testing in high-risk breast and colorectal cancer predisposition genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.