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Staphylococcal Superantigen-Like Protein 10 (SSL10) induces necroptosis through TNFR1 activation of RIPK3-dependent signal pathways

2021-05-05

Abstract excerpt

Staphylococcal aureus ( S. aureus ) infection can lead to a wide range of diseases such as sepsis and pneumonia. Staphylococcal superantigen like (SSL) proteins, specifically expressed by S. aureus , are shown to be involved in immune evasion during S. aureus infection. Here, we show that SSL10, an SSL family protein, exhibits potent cytotoxicity against human cells (HEK 293T and HUVEC) by inducing necroptosis upo...

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Literature Corpus work
cac3e110-2661-5f48-a911-8514950d8e64
DOI
10.21203/rs.3.rs-445262/v1
Open publication

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Staphylococcal Superantigen-Like Protein 10 (SSL10) induces necroptosis through TNFR1 activation of RIPK3-dependent signal pathwaysDOI 10.21203/rs.3.rs-445262/v1
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