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Staphylococcal superantigens in colonization and disease

1 Jan 2012

Abstract excerpt

Superantigens (SAgs) are a family of potent immunostimulatory exotoxins known to be produced by only a few bacterial pathogens, including Staphylococcus aureus. More than 20 distinct SAgs have been characterized from different S. aureus strains and at least 80% of clinical strains harbor at least one SAg gene, although most strains encode many. SAgs have been classically associated with food poisoning and toxic...

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PMID: 22919643
DOI: 10.3389/fcimb.2012.00052

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