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Identification of aberrantly methylated differentially expressed genes in glioblastoma multiforme and their association with patient survival

24 Jul 2019

Abstract excerpt

Glioblastoma multiforme (GBM) is the most malignant primary tumour type of the central nervous system with limited therapeutic options and poor prognosis, and its pathogenic mechanisms have remained to be fully elucidated. Aberrant DNA methylation is involved in multiple biological processes and may contribute to the occurrence and development of GBM by affecting the expression of certain genes. However, the...

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PMID: 31452706
DOI: 10.3892/etm.2019.7807

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